Matthew Perry’s Cause of Death Revealed

Following the death of actor Matthew Perry on October 28 at the age of 54, authorities have disclosed more details about his passing, including the cause of death.

The loved ones of Matthew Perry have received some clarification. Initially deferring the cause of death pending a toxicology report, authorities have now revealed new information regarding the sudden passing of the Friends star on October 28.

The Los Angeles County Medical Examiner declared on December 15 that the cause of death was attributed to “the acute effects of ketamine.” Perry’s death was ruled accidental, primarily associated with drugs and drowning.

According to the autopsy report obtained by E! News on December 15, “high levels” of ketamine in his blood could have led to “lethal effects,” particularly cardiovascular overstimulation and respiratory depression (slow or shallow breathing).

Additional factors contributing to Perry’s passing included drowning, coronary artery disease, and the impact of buprenorphine, a medication used in treating opioid use disorder, as noted by the medical examiner.

The autopsy report revealed that Perry had undergone ketamine infusion therapy for depression and anxiety a week before his death. However, trace amounts of the drug were found in his stomach during his demise, which could not have been from the therapy itself, considering ketamine’s half-life of 3 to 4 hours, or less.

Ketamine therapy typically involves using low doses of the anesthetic medication to manage various mental health conditions, as stated by the Pacific Neuroscience Institute.

Furthermore, Perry’s autopsy indicated no presence of alcohol, methamphetamine, cocaine, heroin, PCP, or fentanyl. The report also highlighted that Perry had reportedly been clean for 19 months before his passing.

The actor, known for his role in “Fools Rush In,” was discovered deceased at his Los Angeles residence on October 28. Authorities responded to an emergency call reporting an unconscious man in a standalone hot tub, according to the city’s fire department captain Erik Scott, who spoke to E! News on October 30.

Scott provided insight into Perry’s final moments and the rescue efforts, mentioning that a bystander had managed to bring Perry’s head above the water before firefighters arrived. However, a medical assessment revealed Perry was already deceased upon the responders’ arrival.

Following Perry’s sudden demise, his former co-stars, including Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc, and David Schwimmer, expressed their sorrow at the loss, paying tribute to the late actor.

Maggie Wheeler, who played Janice, Chandler Bing’s ex-girlfriend on Friends, also shared a heartfelt message for her scene partner on social media, emphasizing the joy Perry brought to many lives during his brief lifetime.

In the months before his death, Perry had been candid about the challenges he faced, notably his ongoing struggle with sobriety, discussing it in his memoir, “Friends, Lovers and the Big Terrible Thing.”

While Perry’s career boasted numerous accolades, he preferred not to be solely defined by his work, emphasizing the value of aiding others through their struggles, stating that assisting people in need was the most significant aspect of his life.

He aimed to live his life proving that his impact on others’ lives would be his lasting legacy, rather than his fame from “Friends.”